Ameliorative Effect of Thymus Oil on Paracetamol Induced Hepato-Renal Toxicity: A Biochemical, Antioxidant and Histopathological Studies
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چکیده
منابع مشابه
Ameliorative effect of Zingiber officinale on diazinon -induced testicular toxicity: A biochemical, histopathological, and immunohistochemical study
Background and objectives: Diazinon (O,O-diethyl O-2-isopropyl-6- methyl pyrimidinyl-4-g-1- phosphorothioate) is one of the organophosphate insecticides for different agricultural and gardening uses, which can be highly toxic. Zingiber officinale(ginger), a spice and herbal medicine, has antioxidant and anti-inflammatory properties. This study has investigated the eff...
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Objective(s): Oxytetracycline (OTC) is a broad spectrum antibiotic widely used for treatment of a wide range of infections. However, its improper human and animal use leads to toxic effects, including hepatonephrotoxicity. Our objective was to evaluate protective effects of Nigella sativa oil (NSO) and/or ascorbic acid (AA), against OTC-induced hepatonephrotoxicity in rabbits. Materials and Me...
متن کاملProtective effect of Triphala Rasayana against paracetamol-induced hepato–renal toxicity in mice
BACKGROUND Paracetamol, a widely used analgesic and antipyretic, is known to cause liver and renal injury in humans when administered in higher and repeated doses that cause acute liver injury. Triphala is a well-known Ayurvedic Rasayana formulation that is prescribed for balancing of Vata, Pitta and Kapha. Traditionally, it is used for the treatment of liver and kidney diseases. OBJECTIVE Th...
متن کاملHistopathological and Molecular Studies on Tramadol Mediated Hepato-Renal Toxicity in Rats
Tramadol, a broadly used opioid in recent years, is an effective analgesic agent for the treatment of moderately severe acute or chronic pain. The liver and kidneys are responsible for the metabolism and excretion of opioids, which may cause hepatotoxicity and nephrotoxicity. The present study was designed to evaluate the toxic effects of tramadol on the liver and kidney of experimental rats. T...
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ژورنال
عنوان ژورنال: Journal of pharmacology & clinical research
سال: 2017
ISSN: 2473-5574
DOI: 10.19080/jpcr.2017.04.555637